Decreased biventricular longitudinal strain in patients with systemic sclerosis is mainly caused by pulmonary hypertension and not by systemic sclerosis per se.
Anthony LindholmRoger HesselstrandGöran RådegranHåkan ArhedenEllen OstenfeldPublished in: Clinical physiology and functional imaging (2019)
Lower GLS is mainly determined by increased pulmonary pressure and not by SSc per se. Low LV and RVFW GLS are indicative of increased mPAP and PVR, which opens for improved non-invasive methods to select patients eligible for right heart catheterization and to monitor the effects of PAH therapy.
Keyphrases
- systemic sclerosis
- interstitial lung disease
- pulmonary hypertension
- end stage renal disease
- ejection fraction
- newly diagnosed
- pulmonary artery
- chronic kidney disease
- stem cells
- cross sectional
- ultrasound guided
- mesenchymal stem cells
- idiopathic pulmonary fibrosis
- left ventricular
- coronary artery
- smoking cessation
- cell therapy
- patient reported