The Role of Nutrients and Diet Characteristics in the Management of Diabetic Foot Ulcers: A Systematic Review.
Kyriaki ApergiCharilaos DimosthenopoulosNikoloas PapanasPublished in: The international journal of lower extremity wounds (2023)
Diabetic foot ulcers (DFUs) are common complications of diabetes mellitus that affect patients' quality of life and pose a burden on the healthcare system. Although malnutrition and specific nutritional deficiencies can seriously impact wound healing in patients with chronic nonhealing wounds, the role of nutrition in the prevention and management of DFUs is still not clear. This review discusses the significance of frequent diet assessment and nutritional education of patients with DFUs with individualized correction of deficiencies and emphasis on adequate protein intake along with correction of vitamins D, C, E, and selenium status. Future research should clarify the impact of nutritional interventions, potentially involving the use of probiotics, zinc, and omega-3 fatty acids, and successfully translating the findings into practical guidelines for use in everyday clinical practice.
Keyphrases
- wound healing
- physical activity
- clinical practice
- end stage renal disease
- fatty acid
- ejection fraction
- weight loss
- newly diagnosed
- healthcare
- chronic kidney disease
- risk factors
- peritoneal dialysis
- prognostic factors
- type diabetes
- quality improvement
- adipose tissue
- metabolic syndrome
- patient reported outcomes
- small molecule