Association of the Fatty Acid Amide Hydrolase C385A Polymorphism With Alcohol Use Severity and Coping Motives in Heavy-Drinking Youth.
Laura M BestJeffrey D WardellRachel F TyndaleMatthew D McPheeBernard Le FollStephen J KishIsabelle BoileauChristian S HendershotPublished in: Alcoholism, clinical and experimental research (2021)
These findings extend previous studies by suggesting that reduced endocannabinoid metabolism may be related to heavier use of alcohol in youth, prior to the onset of chronic drinking problems. Furthermore, differences in negative reinforcement-related drinking could account in part for this association.