Luseogliflozin inhibits high glucose-induced TGF- β 2 expression in mouse cardiomyocytes by suppressing NHE-1 activity.

Naoya OsakaTomomi SaitoMichishige TerasakiMunenori HiromuraTomomi SaitoHironori YashimaYoshie ShiragaRaichi KawakamiMakoto OharaTomoyasu FukuiSho-Ichi Yamagishi

Published in: The Journal of international medical research (2022)

-β2 expression in cardiomyocytes via the suppression of NHE-1 activity.

Keyphrases

high glucose
endothelial cells
poor prognosis
oxidative stress
signaling pathway
stress induced