The Modified Harrington Procedure for Metastatic Peri-Acetabular Bone Lesion Using a Novel Highly Porous Titanium Revision Shell with Long Lever Arm Screw.
Sven FrielerCarsten GebertYannik HanusrichterPeriklis GodoliasMartin WesslingPublished in: Medicina (Kaunas, Lithuania) (2024)
Background and Objectives : Peri-acetabular metastases often lead to significant pain and functional impairment. Surgical interventions, including the Harrington procedure, aim to address these challenges. This study evaluates a modified Harrington procedure using the MUTARS ® PRS ® (Pelvic Revision Shell) with an 8 mm fixation screw for severe acetabular defects resulting from metastatic lesions. Materials and Methods : Retrospective analysis of 12 patients treated between January 2020 and December 2023 was conducted. The procedure involved using the novel MUTARS ® PRS ® with an 8 mm in diameter dome screw (length 70-100 mm). Outcome measures included implant positioning changes, complication rates, functional outcomes, implant longevity, and patient survival. Radiological assessments were performed postoperatively, with follow-ups at 3, 6, 12 months, and annually thereafter. Results : Average follow-up was 15 ± 11 months, with 67% patient survival at 1 year and 44% at 2 years. Implant survivorship remained 100%. Harris Hip Score improved significantly from 37 ± 22 preoperatively to 75 ± 15 at the last follow-up. No revisions involving implant components were reported. Complications occurred in 5 of 12 patients. Overall, PRS ® demonstrates effective osseous ingrowth, high primary stability, immediate full weight-bearing, and low complication rates. Conclusions : PRS ® integrates facilitating osseous ingrowth for preferable long-term outcomes, while efficiently transmitting the weight-bearing load to the intact aspect of the pelvis using a long 8 mm lever screw, enhancing the primary stability of the construct. It proves to be an effective and reproducible technique for managing destructive metastatic lesions of the acetabulum and peri-acetabular region, even in irradiated bone.
Keyphrases
- total hip arthroplasty
- soft tissue
- minimally invasive
- total hip
- total knee arthroplasty
- squamous cell carcinoma
- small cell lung cancer
- end stage renal disease
- physical activity
- case report
- weight loss
- chronic kidney disease
- body mass index
- ejection fraction
- bone mineral density
- chronic pain
- newly diagnosed
- finite element analysis
- peritoneal dialysis
- risk factors
- weight gain
- rectal cancer
- bone loss
- body weight
- spinal cord
- free survival
- neuropathic pain
- body composition
- cross sectional
- bone regeneration