Stroke in Atrial Fibrillation and Other Atrial Dysrhythmias.
Hizir OzdemirDimitrios SagrisGregory Y H LipAzmil H Abdul-RahimPublished in: Current cardiology reports (2023)
-VASc score and clinically relevant biomarkers provides essential tool towards a personalised holistic approach in thromboembolism prevention. Anticoagulation remains the cornerstone of stroke prevention moving from vitamin K antagonists (VKA) to safer non-vitamin K direct oral anticoagulants in the majority of AF patients. Despite the efficacy and safety of oral anticoagulation, still the equilibrium between thrombosis and haemostasis in AF patients remains suboptimal and future directions in anticoagulation and cardiac intervention may provide novel treatment options in stroke prevention. This review summarises the pathophysiologic mechanisms of thromboembolism, aiming the current and potential future perspectives in stroke prevention in AF patients.
Keyphrases
- atrial fibrillation
- direct oral anticoagulants
- left atrial
- oral anticoagulants
- catheter ablation
- end stage renal disease
- left atrial appendage
- heart failure
- newly diagnosed
- chronic kidney disease
- prognostic factors
- randomized controlled trial
- left ventricular
- climate change
- pulmonary embolism
- risk assessment
- patient reported outcomes
- acute coronary syndrome
- aqueous solution
- coronary artery disease