Different clinical entities of the same mutation: a case report of three sisters with Wolfram syndrome and efficacy of dipeptidyl peptidase-4 inhibitor therapy.
Gurkan TarcinHande TuranAydilek Dagdeviren CakirYavuz OzerAyca AykutAsude Alpman DurmazOya ErcanSaadet Olcay EvliyaogluPublished in: Journal of pediatric endocrinology & metabolism : JPEM (2021)
Even in cases with the same mutation, symptoms and findings may widely vary in WS. Remission of diabetes has rarely been reported in WS. Also, this report describes the first trial of a dipeptidyl peptidase-4 inhibitor in a patient with WS which provided a decrease in exogenous insulin need.