Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice.

Shuoshuo LiYajin LiaoYuan DongXiaoheng LiJun LiYong ChengJinbo ChengZeng-Qiang Yuan

Published in: Journal of neuroinflammation (2021)

Our results demonstrated a critical role for microglial activation in PTSD development and a potential therapeutic strategy for the clinical treatment of PTSD in the form of microglial inhibition.

Keyphrases

lipopolysaccharide induced
inflammatory response
lps induced
neuropathic pain
social support
posttraumatic stress disorder
high fat diet induced
type diabetes
adipose tissue
skeletal muscle
combination therapy