Amino acid metabolism in glioma: in vivo MR-spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients.

Seyma AlcicekUlrich PilatusAndrei ManzhurtsevKatharina J WeberMichael W RonellenfitschJoachim P SteinbachElke HattingenKatharina J Wenger

Published in: Journal of neuro-oncology (2024)

Focusing on amino acids in MRS can improve its diagnostic and prognostic value in glioma. Alanine, which is visible at long TE even in the presence of lipids, could be a relevant indicator for overall survival.

Keyphrases

amino acid
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
magnetic resonance
fatty acid
loop mediated isothermal amplification