Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma.
Qian SongJunzhou WuSheng WangSongxiao XuPublished in: Future oncology (London, England) (2021)
Aims: This study aimed to investigate the relationship between perioperative change in neutrophil count and survival of patients with esophageal squamous cell carcinoma. Method: Neutrophil change (Nc) (where Nc = post-surgery neutrophil count - pre-surgery neutrophil count) was counted according to data within 1 week before surgery and 2 weeks after surgery. Patients were divided into two groups, Nc ≥2.60 and Nc <2.60, according to the median of Nc. Results: Multivariate analysis revealed that Nc ≥2.60 was an independent prognostic marker for overall survival. Subgroup analysis suggested that the overall survival of male patients, patients aged ≤60 years, patients without vessel invasion and patients without nerve infiltration was dramatically worse for those with Nc <2.60. Conclusion: Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma after surgery.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- patients undergoing
- acute coronary syndrome
- atrial fibrillation
- percutaneous coronary intervention
- coronary artery bypass
- artificial intelligence
- acute kidney injury
- deep learning
- single cell
- patient reported
- gestational age