Enhancing IgA-mediated neutrophil cytotoxicity against neuroblastoma by CD47 blockade.
Chilam ChanMarjolein C StipMaaike NederendMarco JansenElsemieke PasschierFemke van den HamJudith WienkeGeert van TeteringJeanette H W LeusenPublished in: Journal for immunotherapy of cancer (2024)
These promising results highlight the potential to enhance immunotherapy efficacy against high-risk neuroblastoma through improved neutrophil cytotoxicity by combining IgA therapy with CD47 blockade.