Jeanette H W Leusen (J H W Leusen, Jeanette Leusen)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 32

Top Venues

Journal for immunotherapy of cancer

Journal of immunology (Baltimore, Md. : 1950)

mAbs

Blood advances

TigaTx

Sanquin/CLB (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

TigaTx

Netherlands

CSO

University Medical Center Utrecht Jan 01 2005

Netherlands

associate professor :: Laboratory of Translational Immunology (LTI)

Education History

Sanquin/CLB Jun 01 1991 - Dec 01 1995

Netherlands

PHD :: exp. Bloedcelchemie

Publications

Chilam Chan, Marjolein C Stip, Maaike Nederend, Marco Jansen, Elsemieke Passchier, Femke van den Ham, Judith Wienke, Geert van Tetering, Jeanette H W Leusen
Enhancing IgA-mediated neutrophil cytotoxicity against neuroblastoma by CD47 blockade. Journal for immunotherapy of cancer 12 (5) (2024)
Chilam Chan, J H Marco Jansen, Ilona S T Hendriks, Ida C van der Peet, Meggy E L Verdonschot, Elsemieke M Passchier, Maria Tsioumpekou, Maaike Nederend, Sharon A Klomp, Matthias Peipp, Thomas Valerius, Jeanette H W Leusen, Patricia A Olofsen
Enhancing neutrophil cytotoxicity of a panel of clinical EGFR antibodies by Fc engineering to IgA3.0. Molecular cancer therapeutics (2024)
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette H W Leusen, Mikaela Grönholm, Vincenzo Cerullo
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors. Journal for immunotherapy of cancer 12 (3) (2024)
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette H W Leusen, Mikaela Grönholm, Vincenzo Cerullo
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors. Journal for immunotherapy of cancer 12 (3) (2024)
Connor A Richterich, Meike E W Logtenberg, Marco J H Jansen, Mireille Toebes, Kaspar Bresser, Anne Borst, Anouk P Jurgens, Jeanette H W Leusen, Ton N M Schumacher
ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo. Journal of immunology (Baltimore, Md. : 1950) (2024)
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette H W Leusen, Mikaela Grönholm, Vincenzo Cerullo
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors. Journal for immunotherapy of cancer 12 (3) (2024)
Chilam Chan, Marjolein C Stip, Maaike Nederend, Marco Jansen, Elsemieke Passchier, Femke van den Ham, Judith Wienke, Geert van Tetering, Jeanette H W Leusen
Enhancing IgA-mediated neutrophil cytotoxicity against neuroblastoma by CD47 blockade. Journal for immunotherapy of cancer 12 (5) (2024)
Chilam Chan, Marjolein C Stip, Maaike Nederend, Marco Jansen, Elsemieke Passchier, Femke van den Ham, Judith Wienke, Geert van Tetering, Jeanette H W Leusen
Enhancing IgA-mediated neutrophil cytotoxicity against neuroblastoma by CD47 blockade. Journal for immunotherapy of cancer 12 (5) (2024)
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette H W Leusen, Mikaela Grönholm, Vincenzo Cerullo
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors. Journal for immunotherapy of cancer 12 (3) (2024)
Chilam Chan, Marjolein C Stip, Maaike Nederend, Marco Jansen, Elsemieke Passchier, Femke van den Ham, Judith Wienke, Geert van Tetering, Jeanette H W Leusen
Enhancing IgA-mediated neutrophil cytotoxicity against neuroblastoma by CD47 blockade. Journal for immunotherapy of cancer 12 (5) (2024)
Marjolein C Stip, Mitchell Evers, Maaike Nederend, Chilam Chan, Karli R Reiding, Mirjam J Damen, Albert J R Heck, Sofia Koustoulidou, Ruud Ramakers, Gerard C Krijger, Remmert de Roos, Edouard Souteyrand, Annelisa M Cornel, Miranda P Dierselhuis, Marco Jansen, Mark de Boer, Thomas Valerius, Geert van Tetering, Jeanette H W Leusen, Friederike Meyer-Wentrup
IgA antibody immunotherapy targeting GD2 is effective in preclinical neuroblastoma models. Journal for immunotherapy of cancer 11 (7) (2023)
Marjolein C Stip, J H Marco Jansen, Maaike Nederend, Maria Tsioumpekou, Mitchell Evers, Patricia A Olofsen, Friederike Meyer-Wentrup, Jeanette H W Leusen
Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains. Cancer immunology, immunotherapy : CII (2023)
Maria Tsioumpekou, Daniëlle Krijgsman, Jeanette H W Leusen, Patricia A Olofsen
The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease. Cells 12 (15) (2023)
Biliana Todorova, Ophélie Godon, Eva Conde, Caitlin M Gillis, Bruno Iannascoli, Odile Richard-Le Goff, Daniel Fiole, Lubka T Roumenina, Jeanette H W Leusen, Andrew J Murphy, Lynn E Macdonald, Laurent L Reber, Friederike Jönsson, Pierre Bruhns
IgG Subclass-Dependent Pulmonary Antigen Retention during Acute IgG-Dependent Systemic Anaphylaxis in Mice. Journal of immunology (Baltimore, Md. : 1950) 209 (7) (2022)
Tassilo L A Wachsmann, Anne K Wouters, Dennis F G Remst, Renate S Hagedoorn, Miranda H Meeuwsen, Eline van Diest, Jeanette H W Leusen, Jürgen H E Kuball, J H Frederik Falkenburg, Mirjam H M Heemskerk
Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure. Oncoimmunology 11 (1) (2022)
Patricia A Olofsen, Marjolein C Stip, J H Marco Jansen, Chilam Chan, Maaike Nederend, Ralph G Tieland, Maria Tsioumpekou, Jeanette H W Leusen
Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody. Cells 11 (21) (2022)
Tosca Holtrop, Kevin Budding, Arianne M Brandsma, Jeanette H W Leusen
Targeting the high affinity receptor, FcγRI, in autoimmune disease, neuropathy, and cancer. Immunotherapy advances 2 (1) (2022)
Mitchell Evers, Marjolein Stip, Kaylee Keller, Hanneke Willemen, Maaike Nederend, Marco Jansen, Chilam Chan, Kevin Budding, Stefan Nierkens, Thomas Valerius, Friederike Meyer-Wentrup, Niels Eijkelkamp, Jeanette H W Leusen
Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma. Journal for immunotherapy of cancer 9 (10) (2022)
Firas Hamdan, Erkko O Ylösmäki, Jacopo Chiaro, Yvonne Giannoula, Maeve Long, Manlio Fusciello, Sara Feola, Beatriz Martins, Michaela Feodoroff, Gabriella Antignani, Salvatore Russo, Otto Kari, Moon Lee, Petrus Järvinen, Harry Nisen, Anna Kreutzman, Jeanette H W Leusen, Mohamed El Missiry, Thomas G McWilliams, Mikaela Grönholm, Vincenzo Cerullo
Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids. Journal for immunotherapy of cancer 9 (8) (2022)
Mitchell Evers, Toine Ten Broeke, J H Marco Jansen, Maaike Nederend, Firas Hamdan, Karli R Reiding, Saskia Meyer, Petra Moerer, Iris Brinkman, Thies Rösner, Robert Jan Lebbink, Thomas Valerius, Jeanette H W Leusen
Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies. mAbs 12 (1) (2021)
Sina Bondza, Toine Ten Broeke, Marika Nestor, Jeanette H W Leusen, Jos Buijs
Bivalent binding on cells varies between anti-CD20 antibodies and is dose-dependent. mAbs 12 (1) (2021)
Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette H W Leusen, Jan Terje Andersen
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo. mAbs 13 (1) (2021)
Mitchell Evers, Thies Rösner, Anna Dünkel, J H Marco Jansen, Niklas Baumann, Toine Ten Broeke, Maaike Nederend, Klara Eichholz, Katja Klausz, Karli Reiding, Denis M Schewe, Christian Kellner, Matthias Peipp, Jeanette H W Leusen, Thomas Valerius
The selection of variable regions affects effector mechanisms of IgA antibodies against CD20. Blood advances 5 (19) (2021)
G J J Kierkels, W Scheper, A D Meringa, I Johanna, D X Beringer, A Janssen, M Schiffler, T Aarts-Riemens, L Kramer, T Straetemans, S Heijhuurs, Jeanette H W Leusen, Esther San José, K Fuchs, M Griffioen, J H Falkenburg, Laura Bongiovanni, A de Bruin, D Vargas-Diaz, A F Maarten Altelaar, Albert J R Heck, L D Shultz, Fumihiko Ishikawa, M I Nishimura, Z Sebestyén, J Kuball
Identification of a tumor-specific allo-HLA-restricted γδTCR. Blood advances 3 (19) (2020)
Geert van Tetering, Mitchell Evers, Chilam Chan, Marjolein Stip, Jeanette H W Leusen
Fc Engineering Strategies to Advance IgA Antibodies as Therapeutic Agents. Antibodies (Basel, Switzerland) 9 (4) (2020)
Mitchell Evers, Elizabeth Kruse, Firas Hamdan, Robert Jan Lebbink, Jeanette H W Leusen
Comment on "Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells". Journal of immunology (Baltimore, Md. : 1950) 200 (8) (2019)
Johan M S van der Schoot, Felix L Fennemann, Michael Valente, Yusuf Dölen, Iris M Hagemans, Anouk M D Becker, Camille M Le Gall, Duco van Dalen, Alper Cevirgel, Jaco A C van Bruggen, Melanie Engelfriet, Tomislav Čaval, Arthur E H Bentlage, Marieke F Fransen, Maaike Nederend, Jeanette H W Leusen, Albert J R Heck, Gestur Vidarsson, Carl G Figdor, Martijn Verdoes, Ferenc A Scheeren
Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering. Science advances 5 (8) (2019)
Saskia Meyer, Mitchell Evers, Johannes H M Jansen, Jos Buijs, Blanca Broek, Stephanie E Reitsma, Petra Moerer, Mojtaba Amini, Anna Kretschmer, Toine Ten Broeke, Marcel T den Hartog, Mark Rijke, Christian Klein, Thomas Valerius, Peter Boross, Jeanette H W Leusen
New insights in Type I and II CD20 antibody mechanisms-of-action with a panel of novel CD20 antibodies. British journal of haematology 180 (6) (2018)
Arianne M Brandsma, Samantha L Schwartz, Michael J Wester, Christopher C Valley, Gittan L A Blezer, Gestur Vidarsson, Keith A Lidke, Toine Ten Broeke, Diane S Lidke, Jeanette H W Leusen
Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI. Science signaling 11 (540) (2018)
Shamir R Jacobino, Maaike Nederend, J Frederiek Reijneveld, Daan Augustijn, J H Marco Jansen, Jan Meeldijk, Karli R Reiding, Manfred Wuhrer, Frank E J Coenjaerts, C Erik Hack, Louis J Bont, Jeanette H W Leusen
Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo. mAbs 10 (3) (2018)
Arianne M Brandsma, Toine Ten Broeke, Evelien van Dueren den Hollander, Thomas G Caniels, Tineke Kardol-Hoefnagel, Jürgen Kuball, Jeanette H W Leusen
Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions. Journal of immunology (Baltimore, Md. : 1950) 199 (7) (2017)
Christian H K Lehmann, Anna Baranska, Gordon F Heidkamp, Lukas Heger, Kirsten Neubert, Jennifer J Lühr, Alana Hoffmann, Katharina C Reimer, Christin Brückner, Simone Beck, Michaela Seeling, Melissa Kießling, Didier Soulat, Anne B Krug, Jeffrey V Ravetch, Jeanette H W Leusen, Falk Nimmerjahn, Diana Dudziak
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo. The Journal of experimental medicine 214 (5) (2017)

Jeanette H W Leusen.css-eqlu8i{font-size:small;padding-left:4px;} (J H W Leusen, Jeanette Leusen)

Publication Activity (10 Years)

Top Topics

Top Venues

Jeanette H W Leusen (J H W Leusen, Jeanette Leusen)