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Selenium Deficiency Induces Pathological Cardiac Lipid Metabolic Remodeling and Inflammation.

Chaohua TangShuang LiKai ZhangJing LiYunsheng HanQingyu ZhaoXiaoqing GuoYuchang QinJingdong YinJunmin Zhang
Published in: Molecular nutrition & food research (2022)
The present study identifies a lipid metabolic vulnerability and inflammation initiation pathway via Se deficiency, which may provide targets for human redox imbalance-induced cardiac disease treatment.
Keyphrases
  • oxidative stress
  • endothelial cells
  • left ventricular
  • diabetic rats
  • replacement therapy
  • high glucose
  • fatty acid
  • climate change
  • genome wide
  • induced pluripotent stem cells
  • heart failure
  • atrial fibrillation