Electrophilic derivatives of omega-3 fatty acids counteract lung cancer cell growth.
Liboria SienaChiara CipollinaSerena Di VincenzoMaria FerraroAndreina BrunoMark GjomarkajElisabetta PacePublished in: Cancer chemotherapy and pharmacology (2018)
Data herein provided, demonstrate that 17-oxo-DHA displays antitumor effects in NSCLC cell lines. Of note, the combination of 17-oxo-DHA plus gemcitabine, resulted in stronger anticancer effects compared to gemcitabine alone.