Corticosteroid plus glycyrrhizin therapy for chronic drug- or herb-induced liver injury achieves biochemical and histological improvements: a randomised open-label trial.
Jia-Bo WangAng HuangYijin WangDong JiQing-Sheng LiangJun ZhaoGuangde ZhouShuhong LiuMing NiuYing SunHui TianGuang-Ju TengBin-Xia ChangJing-Feng BiXiao-Xia PengShaojie XinHuan XieXiong MaYi-Min MaoSuthat LiangpunsakulRomil SaxenaGuruprasad P AithalXiao-He XiaoJing-Min ZhaoZheng-Sheng ZouPublished in: Alimentary pharmacology & therapeutics (2022)
This study provides the first clinical evidence that corticosteroid plus glycyrrhizin therapy for chronic DILI with or without AIH-like features can achieve both biochemical response and histological improvements with good safety. (ClinicalTrials.gov, NCT02651350).