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The predictive capacity of polygenic risk scores for disease risk is only moderately influenced by imputation panels tailored to the target population.

Hagai LeviRan ElkonRon Shamir
Published in: Bioinformatics (Oxford, England) (2024)
The source code used for executing the analyses is this paper is available at https://github.com/Shamir-Lab/PRS-imputation-panels.
Keyphrases
  • smoking cessation
  • breast cancer risk