Obesogenic and diabetic effects of CD44 in mice are sexually dimorphic and dependent on genetic background.

Melissa VerHagueJody AlbrightKeri BarronMyungsuk KimBrian J Bennett

Published in: Biology of sex differences (2022)

CD44 was associated with adiposity, liver fat, and glucose in male mice. However, the effects of CD44 on obesity may be independent of TLR4 signaling.

Keyphrases

insulin resistance
type diabetes
high fat diet induced
nk cells
adipose tissue
weight gain
immune response
weight loss
toll like receptor
blood glucose
gene expression
body mass index
fatty acid
wound healing
blood pressure