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Incidence of serious infections in the working-age Japanese adult population with rheumatoid arthritis treated with tumor necrosis factor-α inhibitors and interleukin-6 inhibitors: A nationwide retrospective cohort study.

Ryosuke OtaAtsushi HirataTakeo HataMasami NishiharaMasashi NeoTakahiro Katsumata
Published in: Pharmacotherapy (2024)
The results underscore the lack of evidence to preferentially favor either TNFαi or IL-6i as later-line therapy in the management of bDMARDs-naive RA to mitigate the risk of serious infections.
Keyphrases
  • rheumatoid arthritis
  • disease activity
  • ankylosing spondylitis
  • interstitial lung disease
  • hiv infected
  • cross sectional
  • stem cells
  • smoking cessation