Risk of a first clinical diagnosis of CNS demyelination in relation to Human herpesviruses in the context of Epstein-Barr virus.

HHV-6-DNA positivity and high load (possibly due to inherited HHV-6 chromosomal integration) were associated with increased FCD risk, particularly in association with markers of EBV infection. With growing interest in prevention/management of MS through EBV-related pathways, there should be additional consideration of the role of HHV-6 infection. This article is protected by copyright. All rights reserved.