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Multi-Response Based Personalized Treatment Selection with Data from Crossover Designs for Multiple Treatments.

K B KulasekeraChathura Siriwardhana
Published in: Communications in statistics: Simulation and computation (2019)
In this work we propose a novel method for treatment selection based on individual covariate information when the treatment response is multivariate and data are available from a crossover design. Our method covers any number of treatments and it can be applied for a broad set of models. The proposed method uses a rank aggregation technique to estimate an ordering of treatments based on ranked lists of treatment performance measures such as smooth conditional means and conditional probability of a response for one treatment dominating others. An empirical study demonstrates the performance of the proposed method in finite samples.
Keyphrases
  • healthcare
  • randomized controlled trial
  • clinical trial
  • artificial intelligence
  • double blind
  • social media
  • smoking cessation