Association of immune-related pneumonitis with clinical benefit of anti-programmed cell death-1 monotherapy in advanced non-small cell lung cancer.

Kana OnoHirotaka OnoYukihiro ToiJun SugisakaMari AsoRyohei SaitoSachiko KawanaTomoiki AibaTetsuo OdakaSuguru MatsudaShin SaitoAkane NarumiTakahiro OgasawaraHisashi ShimizuYutaka DomekiKeisuke TerayamaYosuke KawashimaAtsushi NakamuraShinsuke YamandaYuichiro KimuraYoshihiro HondaShunichi Sugawara

Published in: Cancer medicine (2021)

CIP was associated with prolonged PFS and OS. Additionally, 25% of CIP patients did not show any tumor growth for long periods after treatment discontinuation. Careful management of CIP can help in obtaining the best clinical efficacy from anti-PD-1 antibody.

Keyphrases

advanced non small cell lung cancer
end stage renal disease
epidermal growth factor receptor
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
randomized controlled trial
rheumatoid arthritis
tyrosine kinase