Direct Oral Anticoagulants Versus Warfarin for Venous Thromboembolism Prophylaxis in Patients With Nephrotic Syndrome: A Retrospective Cohort Study.

Aminat TijaniEric M CoonsBritta MizukiMiranda DermadyKaterina StanilovaAshley L CaseyMuhannad AlqudsiMariella Gastanaduy Ardem ElmayanAdi BamnolkerJuan Carlos Q Velez

Published in: The Annals of pharmacotherapy (2022)

Use of DOACs for VTE prophylaxis resulted in a nonstatistically significant, but clinically relevant lower rate of major bleeding compared to warfarin. This study provides comparative data showing safe and effective use of DOACs in patients with NS. Prospective, randomized studies are needed to confirm results.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
open label
electronic health record
big data
phase iii
randomized controlled trial
dengue virus
clinical trial
study protocol
oral anticoagulants