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Probing the cell delivery of synthetic diubiquitin chains.

Shaswati MandalAshraf Brik
Published in: Chemical communications (Cambridge, England) (2022)
In this study, the live-cell delivery of structurally different synthetic diubiquitin chains was examined. We found that the combination of structural variations of the Ub chains (intrinsic factors); nature of CPP and CPP-protein linkage (extrinsic factors) influence their delivery.
Keyphrases
  • single cell
  • cell therapy
  • gene expression
  • mesenchymal stem cells
  • small molecule
  • bone marrow
  • hepatitis c virus
  • amino acid
  • protein protein
  • hiv testing