Probing the cell delivery of synthetic diubiquitin chains.
Shaswati MandalAshraf BrikPublished in: Chemical communications (Cambridge, England) (2022)
In this study, the live-cell delivery of structurally different synthetic diubiquitin chains was examined. We found that the combination of structural variations of the Ub chains (intrinsic factors); nature of CPP and CPP-protein linkage (extrinsic factors) influence their delivery.