Effects of Metformin on JNK Signaling Pathway and PD-L1 Expression in Triple Negative Breast Cancer.

Published in: Cancer management and research (2024)

Metformin can inhibit the expression of PD-L1 in triple-negative breast cancer mice and improve the tumor microenvironment, but does not reduce the size of the tumor.

Keyphrases

signaling pathway
poor prognosis
induced apoptosis
pi k akt
epithelial mesenchymal transition
cell death
high fat diet induced
binding protein
type diabetes
wild type
insulin resistance
adipose tissue
skeletal muscle