Long non-coding RNA H19 as a biomarker for hepatocellular carcinoma.
Ángela RojasAntonio Gil-GómezPatricia de la Cruz-OjedaRocío Muñoz-HernándezYolanda Sánchez-TorrijosRocío Gallego-DuránRaquel MillánMaría Carmen RicoRocío Montero-VallejoSheila Gato-ZambranoDouglas Maya-MilesM Teresa FerrerJordi MuntanéMaría José Robles-FríasJavier AmpueroFrancisco J PadilloManuel RomeroPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
LncRNA-H19 expression was increased in CSCs, in liver tissue and plasma of patients with HCC and decreased after partial/complete therapeutic response. Those patients who developed HCC during the follow-up showed higher levels of lncRNA-H19. LncRNA-H19 could constitute a new biomarker of HCC.