Cadmium Toxicity and Health Effects-A Brief Summary.
Angelika Edyta CharkiewiczWioleta Justyna OmeljaniukKarolina NowakMarzena GarleyJacek NiklińskiPublished in: Molecules (Basel, Switzerland) (2023)
Cadmium (Cd) is a ductile metal in the form of a blueish or silvery-white powder. It is naturally found in soil (about 0.2 mg/kg), minerals, and water. Cd belongs to the group of toxic, carcinogenic, and stimulating elements. Its biological half-life in the human body ranges from 16 to even 30 years on average. Some lung diseases (such as emphysema, asthma, and bronchitis) and high blood pressure are thought to be related to slow poisoning. The symptoms of cadmium poisoning may vary depending on the time of exposure, the type of diet, and the age and health status of the exposed people. For non-smokers and non-occupational exposures, the only source of exposure is diet. The FAO/WHO recommends that the tolerable cadmium intake for an adult is approximately 0.4-0.5 mg/week (60-70 µg per day). Cadmium is primarily absorbed through the respiratory system (about 13-19% of Cd from the air), but it can also enter through the digestive system (about 10-44%), when dust is mixed and swallowed with saliva. The amount of accumulated Cd ranges from 0.14 to 3.2 ppm in muscles, 1.8 ppm in bones, and 0.0052 ppm in the blood. People who are most frequently exposed to heavy metals should be continuously monitored in order to maintain a healthy lifestyle, as well as to implement effective preventive measures and improve public health.
Keyphrases
- heavy metals
- public health
- health risk assessment
- blood pressure
- weight loss
- physical activity
- chronic obstructive pulmonary disease
- health risk
- risk assessment
- endothelial cells
- nk cells
- cardiovascular disease
- oxidative stress
- randomized controlled trial
- type diabetes
- cystic fibrosis
- depressive symptoms
- hypertensive patients
- sewage sludge
- skeletal muscle
- insulin resistance
- study protocol
- blood glucose