Cognitive Functioning and Hippocampal Connectivity in Patients With Longstanding Type 1 Diabetes and Apolipoprotein E ε4.

Eelco van DuinkerkenRichard G IJzermanFrederik BarkhofAnnette C MollMichaela DiamantFrank J SnoekMartin Klein

Published in: Diabetes care (2021)

The results may suggest that ApoE-ε4 presence leaves our patients with T1DM more susceptible to cognitive decrements at a younger age, possibly through vascular pathways, warranting further longitudinal studies.

Keyphrases

type diabetes
glycemic control
white matter
cognitive decline
resting state
cross sectional
functional connectivity
insulin resistance
cerebral ischemia
weight loss
essential oil
brain injury
subarachnoid hemorrhage
temporal lobe epilepsy