Ascending Aortic Endograft and Thoracic Aortic Deformation After Ascending Thoracic Endovascular Aortic Repair.
Ga-Young K SuhJohan BondessonYufei D ZhuMichael C NilsonEric E RoselliChristopher P ChengPublished in: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists (2023)
This study quantified local deformations of both stented ascending and native descending aortas to reveal the biomechanical impact of ascending TEVAR on the entire thoracic aorta, and reported that the ascending TEVAR muted cardiac-induced deformation of the stented ascending aorta and native descending aorta. Understanding of in vivo deformations of the stented ascending aorta, aortic arch and descending aorta can inform physicians about the downstream effects of ascending TEVAR. Notable reduction of compliance may lead to cardiac remodeling and long-term systemic complications. This is the first report which included dedicated deformation data regarding ascending aortic endograft from clinical trial.
Keyphrases
- aortic dissection
- pulmonary artery
- coronary artery
- pulmonary hypertension
- pulmonary arterial hypertension
- aortic valve
- clinical trial
- spinal cord
- primary care
- left ventricular
- randomized controlled trial
- open label
- atrial fibrillation
- machine learning
- spinal cord injury
- artificial intelligence
- oxidative stress
- gene expression
- study protocol
- risk factors
- high glucose
- stress induced