Vagus Nerve Stimulation with Mild Stimulation Intensity Exerts Anti-Inflammatory and Neuroprotective Effects in Parkinson's Disease Model Rats.

Ittetsu KinTatsuya SasakiTakao YasuharaMasahiro KamedaTakashi AgariMihoko OkazakiKakeru HosomotoYosuke OkazakiSatoru YabunoSatoshi KawauchiKen KuwaharaJun MorimotoKyohei KinMichiari UmakoshiYousuke TomitaNaoki TajiriCesario Venturina BorlonganIsao Date

Published in: Biomedicines (2021)

VNS with 0.25-0.5 mA intensity has anti-inflammatory and neuroprotective effects on PD model rats induced by 6-OHDA administration. In addition, we were able to confirm the practicality and effectiveness of the new experimental device.

Keyphrases

anti inflammatory
high intensity
randomized controlled trial
systematic review