Expression of dNK cells and their cytokines in twin pregnancies with preeclampsia.

Isabela Karine Rodrigues Agra Adolfo Wenjaw Liao Mara Sandra Hoshida Regina Schultz Marcello P Toscano Rossana Pulcinelli Vieira Francisco Marcelo Zugaib Maria de Lourdes Brizot

Published in: Clinics (Sao Paulo, Brazil) (2019)

A higher maternal serum concentration of both pro- and anti-inflammatory factors was observed in the twin pregnancies in the PEG. However, no difference in placental expression of IL-10 was found between the groups. These findings may suggest that maternal attempts to balance these interleukins were not sufficient to cause a placental response, and this failure may contribute to the development of preeclampsia.

Keyphrases

pregnancy outcomes
anti inflammatory
poor prognosis
pregnant women
birth weight
gestational age
induced apoptosis
early onset
preterm birth
binding protein
drug delivery
cell cycle arrest
long non coding rna
oxidative stress
body mass index
weight gain