A role for the early pregnancy maternal milieu in the intergenerational transmission of obesity.

Emily W Flanagan Jasper Most Abby D Altazan Kristen E Boyle Leanne Maree Redman

Published in: Obesity (Silver Spring, Md.) (2021)

Independent of GWG, MUO resulted in heightened exposure of fetal fat-promoting substrates. Differing metabolic phenotypes may explain heterogeneity of offspring adiposity born to women with obesity.

Keyphrases

insulin resistance
weight gain
metabolic syndrome
weight loss
adipose tissue
high fat diet
high fat diet induced
type diabetes
birth weight
skeletal muscle
single cell
gestational age
fatty acid
body mass index
pregnant women
pregnancy outcomes
physical activity
preterm birth