Prospective insight into the role of benzyl propylene glycoside as a modulator of the cGAS-STING signaling pathway in the management of nonalcoholic fatty pancreas animal model.
Reda M AlbadawyAmany Helmy HasaninSara Hassan AgwaShaimaa H GadallahReham Hussein MohamedEman GomaaMohamed OthmanYahia A YahiaAmani Mohamed Abdel GhaniMarwa MatboliPublished in: Biological research (2023)
benzyl propylene glycoside showed a potential ability to attenuate NAFP development, inhibit pancreatic inflammation and fibrosis and reduce the pathological and metabolic disturbances monitored in the applied NAFP animal model. The detected effect was correlated with modulation of the expression of pancreatic (DDX58, NFκB1, and CHUK mRNAs and miR-1976) panel.