Successful endovascular therapy for cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia.
Yoshihisa FukushimaKenji TakahashiIchiro NakaharaPublished in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2020)
This unique case of cerebral venous sinus thrombosis worsened by occurrence of heparin-induced thrombocytopenia during the treatment finally resulted in excellent outcome highlights effectiveness of emergent endovascular intervention for critical cerebral venous sinus thrombosis resistant to initial medical treatment and of immediate establishment of effective anticoagulant strategy for both of heparin-induced thrombocytopenia and cerebral venous sinus thrombosis. Neuroendovascular therapy for cerebral venous sinus thrombosis using alternative argatroban to heparin for periprocedural anticoagulation might be safe and feasible.
Keyphrases
- venous thromboembolism
- pulmonary embolism
- subarachnoid hemorrhage
- high glucose
- diabetic rats
- randomized controlled trial
- growth factor
- cerebral ischemia
- direct oral anticoagulants
- healthcare
- brain injury
- risk assessment
- systematic review
- drug induced
- endothelial cells
- oxidative stress
- cerebral blood flow
- combination therapy
- blood brain barrier
- smoking cessation