Predicting recurrence in pancreatic neuroendocrine tumours: role of ARX and alternative lengthening of telomeres (ALT).
Vikram DeshpandeRory CrottySteffen RickeltAmaya PankajMarija StojanovaTheodoros P MichelakosYurie SekigamiFilippos KontosPaige H ParrackDeepa T PatilChristopher M HeaphyCristina R FerroneVikram DeshpandePublished in: Histopathology (2023)
Immunohistochemistry for ARX and ALT FISH status may aid in distinguishing biologically indolent cases from aggressive small low-grade PanNETs, and help to identify patients who may preferentially benefit from surgical intervention.