Interaction between Hormonal Receptor Status, Age and Survival in Patients with BRCA1/2 Germline Mutations: A Systematic Review and Meta-Regression.

Arnoud J TempletonLaura Diez GonzalezFrancisco E Vera-BadilloAriadna TibauRobyn GoldsteinBoštjan ŠerugaAmirrtha SrikanthanAtanasio PandiellaEitan AmirAlberto Ocana

Published in: PloS one (2016)

ER-expression appears to be an effect modifier in patients with BRCA1 mutations, but not among those with BRCA2 mutations.

Keyphrases

breast cancer risk
poor prognosis
type diabetes
oxidative stress
estrogen receptor