Cigarette smoking increases the risk of nasopharyngeal carcinoma through the elevated level of IgA antibody against Epstein-Barr virus capsid antigen: A mediation analysis.
Wan-Lun HsuYin-Chu ChienYen-Tsung HuangKelly J YuJenq-Yuh KoChing-Yuan LinYung-An TsouYi-Shing LeuLi-Jen LiaoYen-Liang ChangJia-Ying SuZhiwei LiuCheng-Ping WangShyuang-Der TerngChun-Hung HuaJehn-Chuan LeeTsung-Lin YangChu-Hsing Kate HsiaoMing-Shiang WuMing-Hsui TsaiMing-Jiung LiuPei-Jen LouAllan HildesheimChien-Jen Chennull nullPublished in: Cancer medicine (2020)
This study confirms the association between long-term cigarette smoking and NPC and demonstrates that current smoking is associated with seropositivity of anti-EBV VCA IgA antibodies.