Pilocytic astrocytomas: BRAFV600E and BRAF fusion expression patterns in pediatric and adult age groups.
Hetakshi KuraniMamta GuravOmshree ShettyGirish ChinnaswamyAliasagar MoiyadiTejpal GuptaRakesh JalaliShridar EpariPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2019)
The present study showed overall frequency of 53.5% and 37.3% BRAF alterations in pediatric and adult PCA cases respectively. BRAF fusion in PCA cases showed a different distribution pattern across age groups and locations; while no such differential pattern was observed for BRAFV600E.