MicroRNA-21 increases the expression level of occludin through regulating ROCK1 in prevention of intestinal barrier dysfunction.

Zhihua LiuChao LiShihua ChenHongcheng LinHuan ZhaoMin LiuJinsheng WengTing LiuXiaomei LiChao LeiChen LiYanqiong JiangMary Pat MoyerChunxia YinXinke Zhou

Published in: Journal of cellular biochemistry (2018)

MiR-21 could be a protective factor of intestinal barrier dysfunction, which promoting the expression of TJ protein by targeting ROCK1 in vivo and in vitro.

Keyphrases

poor prognosis
long non coding rna
binding protein
oxidative stress
cell proliferation
long noncoding rna
protein protein