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CRISPR-aided genome engineering for secondary metabolite biosynthesis in Streptomyces.

Yongjae LeeSoonkyu HwangWoori KimJi Hun KimBernhard O PalssonByung Kwan Cho
Published in: Journal of industrial microbiology & biotechnology (2024)
This review summarizes the broad range of CRISPR/Cas applications in Streptomyces for natural product discovery and production.
Keyphrases
  • crispr cas
  • genome editing
  • genome wide
  • small molecule
  • high throughput
  • cell wall
  • dna methylation
  • gene expression