OTX2 regulates CFTR expression during endoderm differentiation and occupies 3' cis-regulatory elements.

Jenny L Kerschner Alekh Paranjapye Monali NandyMazumdar Shiyi Yin Shih-Hsing Leir Ann Harris

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)

These results suggest that a network of interacting cis-regulatory elements recruit OTX2 to the locus to impact CFTR expression during early endoderm differentiation.

Keyphrases

poor prognosis
cystic fibrosis
transcription factor
embryonic stem cells
long non coding rna
protein kinase