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Impact of azithromycin and nitazoxanide on the enteric infections and child growth: Findings from the Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT) trial.

Godfrey GugaEric R HouptSarah ElwoodJie LiuCaroline KimathiRestituta MoshaMariam TemuAthanasia MaroBuliga MujagaNdealilia SwaiSuporn PholwatElizabeth T R McQuadeEsto R MdumaMark D DeBoerJames Platts-Mills
Published in: PloS one (2023)
The antimicrobial intervention of quarterly azithromycin plus or minus nitazoxanide led to only transient decreases in enteric infections with Shigella/EIEC, enteroaggregative E. coli (EAEC), Campylobacter, and Giardia. There was a trend towards improved growth in children infected with Campylobacter that received quarterly azithromycin.
Keyphrases
  • early life
  • randomized controlled trial
  • escherichia coli
  • mental health
  • physical activity
  • clinical trial
  • young adults
  • biofilm formation
  • staphylococcus aureus
  • antimicrobial resistance
  • study protocol
  • brain injury