Lung and Plasma Metabolome in HIV-Associated Obstructive Lung Disease.
Christine WendtSarah SamorodnitskyEric F LockMonica KrukAlison MorrisJanice M LeungKen M KunisakiTimothy J GriffinPublished in: Journal of acquired immune deficiency syndromes (1999) (2022)
Collectively, BALF metabolites differentiate PWH with and without OLD. These included several BALF lipid metabolites. These findings were limited to BALF and were not found in plasma from the same individuals. Phosphatidylcholine, the most common lipid component of surfactant, was the predominant lipid metabolite differentially expressed.