Multicenter evaluation of a high-throughput microarray platform for extensive red blood cell phenotyping and antibody screening.
Christophe MartinaudYgor Neil Hermenegildo LópezIrene Lucea GallegoEstelle FleuriotLuisa MariaBarea GarciaPublished in: Transfusion (2023)
This microarray-based system provides highly comparable results to current CE marked assays. The ability to continuously test 3000 microarrays in 1 day, providing simultaneously both extended RBC phenotyping and antibody detection drives laboratory efficiencies. The results of our study validate the performance of this new technology; however, the percentage of samples without results must be reduced and further analysis is required to interpret the ABS screening performances. This could constitute a real breakthrough in transfusion, making it possible in the long term, on a single platform, to carry out all the analyses necessary for the qualification of donations.