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Safety and efficacy of vedolizumab in pediatric patients with ulcerative colitis: multicenter study in Japan.

Koji YokoyamaYoko YamamotoRyusuke NambuShin-Ichiro HagiwaraDaiki AbukawaTatsuki MizuochiTakahiro KudoTomomitsu SadoNaomi IwataTakashi IshigeItaru IwamaHideki KumagaiKatsuhiro AraiToshiaki Shimizu
Published in: Journal of gastroenterology and hepatology (2023)
VDZ was safe and effective in children with UC. The hematocrit, albumin, and ESR at VDZ initiation might be predictors for VDZ effectiveness. VDZ may be an important option for pediatric patients and can be used as an alternative to immunomodulators.
Keyphrases
  • ulcerative colitis
  • randomized controlled trial
  • systematic review
  • young adults
  • patients with inflammatory bowel disease