Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy.

Pei-Guo WangYu-Ting LiYi PanZhen-Zhu GaoXu-Wen GuanLi Jia Feng-Ting Liu

Published in: Journal of neuro-oncology (2018)

Decreased expression of Bax correlates with poor clinical outcome in patients with gliomas. We propose that Bax protein levels can be used as a reliable prognostic marker for risk-stratify patients with gliomas after curative resection and radiotherapy and/or chemotherapy.

Keyphrases

locally advanced
rectal cancer
poor prognosis
high grade
early stage
induced apoptosis
binding protein
radiation therapy
squamous cell carcinoma
radiation induced
prognostic factors
long non coding rna
amino acid