Advances in Imaging and Automated Quantification of Pulmonary Diseases in Non-neoplastic Diseases.

Histological examination has always been the gold standard for the detection and quantification of lung remodeling. However, this method has some limitations regarding the invasiveness of tissue acquisition. Quantitative imaging methods enable the acquisition of valuable information on lung structure and function without the removal of tissue from the body; thus, they are useful for disease identification and follow-up. This article reviews the various quantitative imaging modalities used currently for the non-invasive study of chronic obstructive pulmonary disease, asthma, and interstitial lung diseases. Some promising computer-aided diagnosis methods are also described.