Long-term high-protein diet intake reverts weight gain and attenuates metabolic dysfunction on high-sucrose-fed adult rats.
Rosângela Maria Lopes SousaNathalee Liberal Xavier RibeiroBruno Araújo Serra PintoJonas Rodrigues SanchesMariana Uchôa da SilvaCaio Fernando Ferreira CoêlhoLucas Martins FrançaJosé Albuquerque de Figueiredo NetoAntonio Marcus de Andrade PaesPublished in: Nutrition & metabolism (2018)
Our data showed that 12-week intake of an isocaloric moderately high-protein diet consistently restored high-sucrose-induced central adiposity and obesity in addition to the attenuation of other important metabolic outcomes, such as improvement of glucolipid homeostasis associated to increased insulin sensitivity and reversal of hepatic steatosis. On the other hand, simple withdrawal from high-sucrose consumption also promoted the abovementioned metabolic outcomes with no impact on body weight.