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CSF Biomarkers in Longitudinal Alzheimer Disease Cohorts: Pre-Analytic Challenges.

Erin M JonaitisBeckie JeffersMonica VandenLangenbergYue MaCarol Van HulleRebecca LanghoughLianlian DuNathaniel A ChinRobert J PrzybelskiKirk J HoganBradley T ChristianTobey J BetthauserOzioma C OkonkwoBarbara B BendlinSanjay AsthanaCynthia M CarlssonSterling C Johnson
Published in: Clinical chemistry (2024)
Under real-world conditions, the Elecsys platform had high repeatability. However, strong effects of pre-analytic factors suggest caution in drawing longitudinal inferences.
Keyphrases
  • cross sectional
  • mild cognitive impairment
  • high throughput
  • cerebrospinal fluid
  • single cell