CSF Biomarkers in Longitudinal Alzheimer Disease Cohorts: Pre-Analytic Challenges.

Erin M JonaitisBeckie JeffersMonica VandenLangenbergYue MaCarol Van HulleRebecca LanghoughLianlian DuNathaniel A ChinRobert J PrzybelskiKirk J HoganBradley T ChristianTobey J BetthauserOzioma C OkonkwoBarbara B BendlinSanjay AsthanaCynthia M CarlssonSterling C Johnson

Published in: Clinical chemistry (2024)

Under real-world conditions, the Elecsys platform had high repeatability. However, strong effects of pre-analytic factors suggest caution in drawing longitudinal inferences.

Keyphrases

cross sectional
mild cognitive impairment
high throughput
cerebrospinal fluid
single cell