Rapid detection of Mucorales in human blood and urine samples by functionalised Heusler magnetic nanoparticle assisted customized loop mediated isothermal amplification.
Rahul RoyGagandeep SinghUjjwal Ranjan DahiyaMragnayani PandeyImmaculata XessDinesh KalyanasundaramPublished in: Medical mycology (2024)
Early Mucormycosis detection is crucial, as current lab tests from blood and urine lack sensitivity and take days for confirmation despite rapid progression and severe complications. Our developed technique enables the confirmation of Mucormycosis infection in less than 45 minutes, focusing specifically on the RT-LAMP process. Consequently, this research offers a viable technique for quickly identifying Mucormycosis from isolated DNA of blood and urine samples instead of invasive tissue samples.