The anti-inflammatory effect of topical tofacitinib on immediate and late-phase cutaneous allergic reactions in dogs: a placebo-controlled pilot study.
Amanda BlubaughDaniel RissiDeborah ElderTara DenleySitka Eguiluz-HernandezFrane BanovicPublished in: Veterinary dermatology (2018)
Our observations suggest that topical tofacitinib exerts an inhibitory effect on activated canine skin-emigrating immune cells; this drug should be investigated further as a topical immunosuppressive drug in dogs.
Keyphrases
- wound healing
- rheumatoid arthritis
- anti inflammatory
- placebo controlled
- ulcerative colitis
- double blind
- adverse drug
- randomized controlled trial
- clinical trial
- soft tissue
- squamous cell carcinoma
- emergency department
- drug induced
- phase ii
- phase ii study
- mass spectrometry
- high resolution
- phase iii
- open label
- atopic dermatitis
- electronic health record